Wikipédia

Usuário(a):MikutoH/T/1

< Usuário(a):MikutoH | T

Canais iônicos pred

editar

modulation 5ht

editar


Binding profiles

editar
Binding profiles of MRIs at human MATs[1]
Compound SERT NET DAT Type Class
Amfonelic acid ND ND 207 DRI Stimulant
Amineptine*[2][3] >100,000 (rat) 10,000 (rat) 1,000–1,400 (rat) DRI Stimulant
Amitriptyline 4.30 35 3,250 SNRI TCA
Amoxapine 58 16.0 4,310 SNRI TeCA
Amphetamine >100,000 ND ND NDRA Stimulant
  D-Amphetamine >100,000 530 2,900 NDRA Stimulant
  L-Amphetamine >100,000 ND ND NRA Stimulant
Atomoxetine 77 5 1,451 NRI Stimulant
Bupropion 9,100 52,000 520 NDRI Stimulant
Butriptyline 1,360 5,100 3,940 N/A (IA) TCA
Chlorphenamine 15.2 1,440 1,060 SRI Antihistamine
Citalopram 1.16 4,070 28,100 SRI SSRI
  Escitalopram[4] 1.1 7,841 27,410 SRI SSRI
Clomipramine 0.28 38 2,190 SNRI TCA
Cocaethylene[5] 3,878 >10,000 555 SDRI Stimulant
Cocaine[5] 304 779 478 SNDRI Stimulant
Cocaine[6] 313±17 (IC50) 292±34 (IC50) 211±19 (IC50) SNDRI Stimulant
Desipramine 17.6 0.83 3,190 SNRI TCA
Desmethylcitalopram 3.6 1,820 18,300 SRI SSRI
Desmethylsertraline 3.0 390 129 SRI SSRI
Desmethylsibutramine[7] 15 20 49 SNDRI SNRI
  (R)-Desmethylsibutramine 44 4 12 SNDRI SNRI
  (S)-Desmethylsibutramine 9,200 870 180 SNDRI SNRI
Desoxypipradrol[8] 53,700 550 50 NDRI Stimulant
Desvenlafaxine*[9] 47 531 ND SNRI SNRI
Didesmethylsibutramine[7] 20 15 45 SNDRI SNRI
  (R)-Didesmethylsibutramine 140 13 8.9 SNDRI SNRI
  (S)-Didesmethylsibutramine 4,300 62 12 SNDRI SNRI
Diphenhydramine 3,800 960 2,200 N/A (IA) Antihistamine
Dosulepin (dothiepin) 8.6 46 5,310 SNRI TCA
Doxepin 68 29.5 12,100 SNRI TCA
Duloxetine*[10] 3.7 20 439 SNRI SNRI
Etoperidone 890 20,000 52,000 SRI SARI
Femoxetine 11.0 760 2,050 SRI SSRI
Fluoxetine 0.81 240 3,600 SRI SSRI
Fluvoxamine 2.2 1,300 9,200 SRI SSRI
GBR-12935[5] 289 277 4.90 DRI Stimulant
Hydroxybupropion[11] ND 1.7 (IC50) >10 (IC50) NDRI Stimulant
Imipramine 1.40 37 8,500 SNRI TCA
Indatraline[5] 3.10 12.6 1.90 SNDRI Stimulant
Iprindole 1,620 1,262 6,530 N/A (IA) TCA
Lofepramine 70 5.4 18,000 SNRI TCA
Maprotiline 5,800 11.1 1,000 NRI TeCA
Mazindol 39 0.45 8.1 NDRI Stimulant
MDPV[12] 3,349 26 4.1 NDRI Stimulant
Methamphetamine >100,000 ND ND NDRA Stimulant
  D-Methamphetamine >100,000 660 2,800 NDRA Stimulant
  L-Methamphetamine >100,000 ND ND NRA Stimulant
Methylphenidate >10,000 788 121 NDRI Stimulant
  D-Methylphenidate >10,000 206 161 NDRI Stimulant
  L-Methylphenidate >6,700 >10,000 2,250 NDRI Stimulant
Mianserin 4,000 71 9,400 NRI TeCA
Milnacipran*[10] 151 68 >100,000 SNRI SNRI
  Levomilnacipran*[13] 19.0 10.5 >100,000 SNRI SNRI
Mirtazapine >100,000 4,600 >100,000 N/A (IA) TeCA
Modafinil*[14] >50,000 136,000 4,043 DRI Stimulant
Nefazodone 200 360 360 SNDRI SARI
Nefopam[15] 29 33 531 SNDRI Analgesic
Nisoxetine[5] 427 2.3 1,235 NRI Stimulant
Nomifensine 1,010 15.6 56 NDRI Stimulant
Norfluoxetine 1.47 1,426 420 SRI SSRI
Nortriptyline 18 4.37 1,140 SNRI TCA
Oxaprotiline 3,900 4.9 4,340 NRI TeCA
Paroxetine 0.13 40 490 SRI SSRI
Protriptyline 19.6 1.41 2,100 SNRI TCA
Reboxetine[16] 129 1.1 >10,000 NRI Stimulant
Sertraline 0.29 420 25 SRI SSRI
Sibutramine[7] 298–2,800 350–5,451 943–1,200 SNDRI SNRI
Trazodone 160 8,500 7,400 SRI SARI
Trimipramine 149 2,450 3,780 SRI TCA
Vanoxerine[5] 73.2 79.2 4.3 DRI Stimulant
Venlafaxine*[10] 145 1,420 3,070 SNRI SNRI
Vilazodone*[17] 0.2 ~60 ND SRI SMS
Viloxazine 17,300 155 >100,000 NRI Stimulant
Vortioxetine*[18] 5.4 890 (rat) 140 (rat) SRI SMS
Zimelidine 152 9,400 11,700 SRI SSRI
Values are Ki (nM) or, in some cases (*), IC50 (nM). The smaller the value, the more strongly the
drug binds to or inhibits the transporter.

Infocaixes

editar

VT Predefinição:Info/Química

Caixa pequena 8cm

editar 
{{Chembox new
| ImageFile  = 
| ImageSize  = 
| IUPACName  = 
| OtherNames = 
| Section1 = {{Chembox Identifiers
|   CASNo    = 
|   PubChem  = 
|   SMILES   = 
  }}
| Section2 = {{Chembox Properties
|   Formula    = 
|   MolarMass  = 
|   Appearance = 
|   Density    = 
|   MeltingPt  = 
|   BoilingPt  = 
|   Solubility = 
  }}
| Section3 = {{Chembox Hazards
|   MainHazards  = 
|   FlashPt      = 
|   Autoignition = 
  }}
}}

Caixa média em cima do muro

editar 
{{Info/Química
| ImageFile      = MDMA (simple).svg
| ImageSize      = 
| ImageFile1     = MDMA molecule from xtal ball.png
| ImageSize1     = 
| IUPACName      = (''RS'')-1-(1,3-Benzodioxol-5-il)-''N''-metilpropan-2-amina
| OtherNames     = Midomafetamina<ref name=INN>{{cite news|title=FDA Substance Registration System|url=https://fdasis.nlm.nih.gov/srs/unii/KE1SEN21RM|access-date=31 August 2017|publisher=United States National Library of Medicine}}</ref>
| Section1       = {{Chembox Identifiers
| Abbreviations  = MDMA
| CASNo          = 50-11-3
| PubChem        = 1615
| SMILES         =  
| StdInChI =  
| UNII           = KE1SEN21RM
| MeSHName       =   
| ChemSpiderID   = 3957
| KEGG           = D11172
| ChEBI          = 31827
| ATCCode_prefix = 
| ATCCode_suffix = 
| ATC_Supplemental =
| DrugBank       =
| DCB            = 
}}
| Section2      = {{Chembox Properties
| Formula       =
| C=11 | H=15 | N=1 | O=2
| MolarMass     = 
| Appearance    = 
| Density       = 
| MeltingPt     = 
| Melting_notes = 
| BoilingPt     = 
| Boiling_notes = 
| Solubility    = 
| SolubleOther  = 
| Solvent       = 
 }}
| Section3      = {{Chembox Pharmacology
| AdminRoutes   = 
| Bioavail      = 
| Metabolism    = 
| HalfLife      = 
| ProteinBound  =
| Excretion     = 
| Volume_de_distribuição = 
| Depuração     = 
| Concentrações_máximas =
| Legal_status  = 
| Legal_US      = 
| Legal_BR      = 
 }}
| Section4      = {{Chembox Hazards
| RPhrases      = 
| SPhrases      = 
| LD50          = }}
|Section5       =
|fundo          = fármaco
}}

caixa media 2?

editar 
<td>
{{chembox new
| ImageFile = 
| ImageSize = 
| IUPACName = 
| OtherNames = 
| Section1 = {{Chembox Identifiers
| Abbreviations = 
| CASNo = 
| EINECS = 
| PubChem = 
| SMILES = 
| InChI = 
| RTECS =
| MeSHName =
| ChEBI =
| KEGG = 
| ATCCode_prefix = 
| ATCCode_suffix = 
| ATC_Supplemental =}}
| Section2 = {{Chembox Properties
| Formula = 
| MolarMass =
| Appearance =
| Density = 
| MeltingPt = 
| Melting_notes =
| BoilingPt = 
| Boiling_notes = 
| Solubility = 
| SolubleOther = 
| Solvent = 
| pKa = 
| pKb = }}
| Section7 = {{Chembox Hazards
| EUClass = 
| EUIndex = 
| MainHazards = 
| NFPA-H = 
| NFPA-F = 
| NFPA-R = 
| NFPA-O =
| RPhrases = 
| SPhrases = 
| RSPhrases =
| FlashPt = 
| Autoignition = 
| ExploLimits = 
| PEL = }}
}}

caixona tamanho médio grande

editar 
<td>
{{chembox new
| ImageFile = 
| ImageSize = 
| IUPACName = 
| SystematicName = 
| OtherNames = 
| Section1 = {{Chembox Identifiers
| Abbreviations = 
| CASNo = 
| EINECS = 
| EINECSCASNO = 
| PubChem = 
| SMILES = 
| InChI = 
| RTECS = 
| MeSHName =
| ChEBI =
| KEGG = 
| ATCCode_prefix = 
| ATCCode_suffix = 
| ATC_Supplemental =
| DrugBank = }}
| Section2 = {{Chembox Properties
| Formula = 
| MolarMass = 
| Appearance = 
| Density = 
| MeltingPt = 
| Melting_notes = 
| BoilingPt = 
| Boiling_notes = 
| Solubility = 
| SolubleOther = 
| Solvent = 
| LogP = 
| VaporPressure = 
| HenryConstant = 
| AtmosphericOHRateConstant = 
| pKa = 
| pKb = }}
| Section3 = {{Chembox Structure
| CrystalStruct = 
| Coordination = 
| MolShape = }}
| Section4 = {{Chembox Thermochemistry
| DeltaHf = 
| DeltaHc = 
| Entropy = 
| HeatCapacity = }}
| Section5 = {{Chembox Pharmacology
| AdminRoutes = 
| Bioavail = 
| Metabolism = 
| HalfLife = 
| ProteinBound =
| Excretion = 
| Legal_status = 
| Legal_US = 
| Legal_UK = 
| Legal_AU = 
| Legal_CA = 
| PregCat = 
| PregCat_AU = 
| PregCat_US = }}
| Section6 = {{Chembox Explosive
| ShockSens = 
| FrictionSens = 
| ExplosiveV = 
| REFactor = }}
| Section7 = {{Chembox Hazards
| EUClass = 
| EUIndex = 
| MainHazards = 
| NFPA-H = 
| NFPA-F = 
| NFPA-R = 
| NFPA-O = 
| RPhrases = 
| SPhrases = 
| RSPhrases = 
| FlashPt = 
| Autoignition = 
| ExploLimits = 
| PEL = 
| LD50 = }}
| Section8 = {{Chembox Related
| OtherAnions = 
| OtherCations = 
| OtherFunctn = 
| Function = 
| OtherCpds = }}
}}

caixona dupla hippie flippy speed ball

editar 
{{chembox new
| ImageFile = 
| ImageSize = 
| IUPACName = 
| SystematicName = 
| OtherNames = 
| Section1 = {{Chembox Identifiers
| Abbreviations = 
| CASNo = 
| EINECS = 
| EINECSCASNO = 
| PubChem = 
| SMILES = 
| InChI = 
| RTECS = 
| MeSHName =
| ChEBI =
| KEGG = 
| ATCCode_prefix = 
| ATCCode_suffix = 
| ATC_Supplemental =
| DrugBank = }}
| Section2 = {{Chembox Properties
| Formula = 
| MolarMass = 
| Appearance = 
| Density = 
| MeltingPt = 
| Melting_notes = 
| BoilingPt = 
| Boiling_notes = 
| Solubility = 
| SolubleOther = 
| Solvent = 
| LogP = 
| VaporPressure = 
| HenryConstant = 
| AtmosphericOHRateConstant = 
| pKa = 
| pKb = }}
| Section3 = {{Chembox Structure
| CrystalStruct = 
| Coordination = 
| MolShape = }}
| Section4 = {{Chembox Thermochemistry
| DeltaHf = 
| DeltaHc = 
| Entropy = 
| HeatCapacity = }}
| Section5 = {{Chembox Pharmacology
| AdminRoutes = 
| Bioavail = 
| Metabolism = 
| HalfLife = 
| ProteinBound =
| Excretion = 
| Legal_status = 
| Legal_US = 
| Legal_UK = 
| Legal_AU = 
| Legal_CA = 
| PregCat = 
| PregCat_AU = 
| PregCat_US = }}
| Section6 = {{Chembox Explosive
| ShockSens = 
| FrictionSens = 
| ExplosiveV = 
| REFactor = }}
| Section7 = {{Chembox Hazards
| EUClass = 
| EUIndex = 
| MainHazards = 
| NFPA-H = 
| NFPA-F = 
| NFPA-R = 
| NFPA-O = 
| RPhrases = 
| SPhrases = 
| RSPhrases = 
| FlashPt = 
| Autoignition = 
| ExploLimits = 
| PEL = 
| LD50 = }}
| Section8 = {{Chembox Related
| OtherAnions = 
| OtherCations = 
| OtherFunctn = 
| Function = 
| OtherCpds = }}
}}

Nome da predefinição
* nome_do_ficheiro.svg (e não [[nome_do_ficheiro.svg]]
* tamanho da imagem (exemplo: ImageSize=100px, default=200px)
* nome IUPAC
* nome sistemático
* outro nome
Secção Identificadores - Números padrão, etc.
* quaisquer abreviaturas
* Número CAS, ligações a eMolecules
* EINECS, ligações ao ecb; a URL é http://ecb.jrc.it/esis/index.php?GENRE=ECNO&ENTREE=
* também EINECS, mas a URL é http://ecb.jrc.it/esis/index.php?GENRE=CASNO&ENTREE=
* PubChem, ligações à pubchem, através do número CID (''Compound identification number''). Para passar a identificação do número SID (''Substance identification number''), utilizar o formato ''n/SID'', por exemplo, 96024416/SID
* SMILES, sem ligações
* InChI, sem ligações
* RTECS, sem ligações
* Medical Subject Headings, ligações à NIH
* ChEBI, ligações ao EBI
* KEGG, ligações a genome.ad.jp
* prefixo ATCCode (primeiros três caracteres), ligação interna
* sufixo ATCCode (últimos quatro caracteres), ligações ATC completas à WHO C.C.
* Outros códigos ATC (use a predefinição {{ATC}})
* Banco de dados da Universidade de Alberta com dados a respeito de medicamentos
Secção propriedades - propriedades físicas
* fórmula molecular
* massa molar, incluindo unidades
* aparência física
* densidade
* ponto de fusão, incluindo unidades
* notas sobre o ponto de fusão
* ponto de ebulição, incluindo unidades
* notas sobre o ponto de ebulição
* solubilidade em água
* solubilidade noutros solventes, usado em conjunto com o campo seguinte
* em que solvente é solúvel
* coeficiente de partição
* pressão de vapor
* constante da lei de Henry (kH)
* Atmospheric OH rate constant
* pKa
* pKb
Secção Estrutura - informação sobre a estrutura cristalina
* Estrutura cristalina
* Coordenação
* Forma molecular
Secção termoquímica - propriedades termoquímicas
* Delta Hf
* Delta Hc
* Entropia
* capacidade calorífica
Secção farmacologia - dados farmacológicos
* vias de administração
* Biodisponibilidade
* Metabolismo
* Semi-vida
* Ligação a proteínas
* Excreção
* estatuto legal
* estatuto legal nos EUA
* estatuto legal no Reino Unido
* estatuto legal na Austrália
* Legal status in CA
* Pregnacy Category
* Pregnacy Category in US
* Pregnacy Category in AU
Secção Explosivos - propriedades explosivas
* sensibilidade a choques
* sensibilidade a fricção
* explosividade
* factor RE
Secção Perigos - perigos associados
* Classe EU 
* Índice EU 
* Principais perigos
* NFPA-H - Saúde
* NFPA-F - Fogo
* NFPA-R - Reactividade
* NFPA-O - um dos parâmetros  W, OX, COR, ALK, ACID, CRYO, RA, ou vazio
* Frases R - use a predefinição {{R}} para este campo
* Frases S - use a predefinição {{S}} para este campo
* Frases R e S - ou use a combinação dos dois campos acima
* ponto de fulgor
* Autoignição
* limites de explosividade
* PEL
* Dose letal mediana
Secção Relacionados - Compostos relacionados, etc
* outros aniões
* outros catiões
* outra função - funciona em conjunto com o campo seguinte
* Função - a função extra
* outros compostos - secção "ver também"
-fim

X

editar

<!--BetacommandBot Exclude--><!--Please do NOT subst this template. If you see this text in a document, the template 'chembox new' has been substituted. In that case, please copy-and-paste the unsubstituted template from [[template:chembox new]], move the data from here into that template, and remove the old template data, thank you! -->{| class="toccolours" style="width: 300px; float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;" ! {{Chembox header|fundo=}} | {{#if:|{{{Name}}}|{{PAGENAME}}}}<br><small>[[Wikipedia:Aviso médico|Alerta sobre risco à saúde]]</small>{{#if:|{{{Reference}}} }} |- fotonome {{#if:| {{Chembox image|par_name={{#if:|ImageFile }} |par_value={{#if:|{{{ImageFile}}} }}|par_size={{#if:|{{{ImageSize}}}|200px}} }} ■ {{Chembox image|par_name={{#if:|ImageFile }} |par_value={{#if:|{{{ImageFile1}}} }}|par_size={{#if:|{{{ImageSize1}}}|200px}} }}■ {{Chembox image sbs|par_nameL={{#if:|ImageFileL }} |par_valueL={{#if:|{{{ImageFileL1}}} }}|par_sizeL={{#if:|{{{ImageSizeL1}}}|100px}} | par_nameR={{#if:|ImageFileR }} |par_valueR={{#if:|{{{ImageFileR1}}} }}|par_sizeR={{#if:|{{{ImageSizeR1}}}|100px}} }}■ {{Chembox image|par_name={{#if:|ImageFile }} |par_value={{#if:|{{{ImageFile2}}} }}|par_size={{#if:|{{{ImageSize2}}}|200px}} }} ■ {{Chembox image|par_name={{#if:|ImageFile }} |par_value={{#if: |{{{ImageFile3}}} }}|par_size={{#if:|{{{ImageSize3}}}|200px}} }}■ {{Chembox image|par_name={{#if:|ImageFile }} |par_value={{#if: |{{{ImageFile4}}} }}|par_size={{#if:|{{{ImageSize4}}}|200px}} }}■ {{Chembox image sbs|par_nameL={{#if:|ImageFileL }} |par_valueL={{#if:|{{{ImageFileL2}}} }}|par_sizeL={{#if:|{{{ImageSizeL2}}}|100px}} | par_nameR={{#if:|ImageFileR }} |par_valueR={{#if:|{{{ImageFileR2}}} }}|par_sizeR={{#if:|{{{ImageSizeR2}}}|100px}} }} | ■ {{#ifexist:Image:{{PAGENAME}}.svg|{{Chembox image|par_name=ImageFile|par_value={{PAGENAME}}.svg|par_size={{#if:|{{{ImageSize}}}|200px}} }} |■ {{#ifexist:Image:{{PAGENAME}}.png|{{Chembox image|par_name=ImageFile|par_value={{PAGENAME}}.png|par_size={{#if:|{{{ImageSize}}}|200px}} }} | ■ {{#ifexist:Image:{{PAGENAME}}.gif|{{Chembox image|par_name=ImageFile|par_value={{PAGENAME}}.gif|par_size={{#if:|{{{ImageSize}}}|200px}} }} | ■ {{#ifexist:Image:{{PAGENAME}}.jpg|{{Chembox image|par_name=ImageFile|par_value={{PAGENAME}}.jpg|par_size={{#if:|{{{ImageSize}}}|200px}} }} | ■ [[Categoria:!Páginas sobre química que necessitam de imagem]] }} }} }} }}■ }} ( ͡❛ ͜ʖ ͡❛) ■■■■■■■ ■■■■■■■ ( ͡❛ ͜ʖ ͡❛) ( ͡❛ ͜ʖ ͡❛) ■■■■■■■ ■■■■■■■ ( ͡❛ ͜ʖ ͡❛) ( ͡❛ ͜ʖ ͡❛) ■■■■■■■ ■■■■■■■ ( ͡❛ ͜ʖ ͡❛) clinical data {{Chembox entry|par_name={{#if:|IUPACName }} |par_value={{#if:|{{{IUPACName}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|SystematicName }} |par_value={{#if:|{{{SystematicName}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|OtherNames }} |par_value={{#if:|{{{OtherNames}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|Abbreviations }}|par_value={{#if:|{{{Abbreviations}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|Formula }} |par_value={{#if:|{{{Formula}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|MolarMass }} |par_value={{#if:|{{{MolarMass}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|CASNo }} |par_value={{#if:|{{{CASNo}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|Density }} |par_value={{#if:|{{{Density}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|Solubility }} |par_value={{#if:|{{{Solubility}}} }}|par_var_label={{#if:|{{{Solvent}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|MeltingPt }} |par_value={{#if:|{{{MeltingPt}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|BoilingPt }} |par_value={{#if:|{{{BoilingPt}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|LogP }} |par_value={{#if:|{{{LogP}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|VaporPressure }}|par_value={{#if:|{{{VaporPressure}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|HenryConstant }}|par_value={{#if:|{{{HenryConstant}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|AtmosphericOHRateConstant }}|par_value={{#if:|{{{AtmosphericOHRateConstant}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|pKa }} |par_value={{#if:|{{{pKa}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|pKb }} |par_value={{#if:|{{{pKb}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|IsoelectricPt }}|par_value={{#if:|{{{IsoelectricPt}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|DeltaHf }} |par_value={{#if:|{{{DeltaHf}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|DeltaHc }} |par_value={{#if:|{{{DeltaHc}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|EINECS }} |par_value={{#if:|{{{EINECS}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|EINECSCASNO }} |par_value={{#if:|{{{EINECSCASNO}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|PubChem }} |par_value={{#if:|{{{PubChem}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|SMILES }} |par_value={{#if:|{{{SMILES}}} }} }}■■■■■■■ 1 {{Chembox entry|par_name={{#if:|InChI }} |par_value={{#if:|{{{InChI}}} }} }}■■■■■■■ {{Chembox Supplement}} | {{Chembox header|fundo=}} | <small>'''Exceto onde denotado, os dados referem-se a<br/> materiais sob [[condições normais de temperatura e pressão]]'''<br/>'''[[Wikipedia:Informação nas infocaixas de química|Referências e avisos gerais sobre esta caixa]].'''<br>'''[[Wikipedia:Aviso médico|Alerta sobre risco à saúde]].''' </small> |- |}

  1. ↑ Tatsumi M, Groshan K, Blakely RD, Richelson E (1997). «Pharmacological profile of antidepressants and related compounds at human monoamine transporters» (PDF). Eur. J. Pharmacol. 340 (2–3): 249–58. PMID 9537821. doi:10.1016/s0014-2999(97)01393-9 [ligação inativa]
  2. ↑ Ceci A, Garattini S, Gobbi M, Mennini T (1986). «Effect of long term amineptine treatment on pre- and postsynaptic mechanisms in rat brain». Br. J. Pharmacol. 88 (1): 269–75. PMC 1917102 . PMID 3708219. doi:10.1111/j.1476-5381.1986.tb09495.x 
  3. ↑ Garattini S, Mennini T (1989). «Pharmacology of amineptine: synthesis and updating». Clin Neuropharmacol. 12 Suppl 2: S13–8. PMID 2698268. doi:10.1097/00002826-198912002-00003 
  4. ↑ Owens JM, Knight DL, Nemeroff CB (2002). «[Second generation SSRIS: human monoamine transporter binding profile of escitalopram and R-fluoxetine]». Encephale (em francês). 28 (4): 350–5. PMID 12232544 
  5. ↑ a b c d e f Rothman RB, Baumann MH (2003). «Monoamine transporters and psychostimulant drugs». Eur. J. Pharmacol. 479 (1–3): 23–40. PMID 14612135. doi:10.1016/j.ejphar.2003.08.054 
  6. ↑ http://www.emcdda.europa.eu/system/files/publications/1814/TDAS15001ENN.pdf Predefinição:Bare URL PDF
  7. ↑ a b c Nisoli E, Carruba MO (2000). «An assessment of the safety and efficacy of sibutramine, an anti-obesity drug with a novel mechanism of action». Obes Rev. 1 (2): 127–39. PMID 12119986. doi:10.1046/j.1467-789x.2000.00020.x 
  8. ↑ Iversen L, Gibbons S, Treble R, Setola V, Huang XP, Roth BL (2013). «Neurochemical profiles of some novel psychoactive substances». Eur. J. Pharmacol. 700 (1–3): 147–51. PMC 3582025 . PMID 23261499. doi:10.1016/j.ejphar.2012.12.006 
  9. ↑ Deecher DC, Beyer CE, Johnston G, Bray J, Shah S, Abou-Gharbia M, Andree TH (2006). «Desvenlafaxine succinate: A new serotonin and norepinephrine reuptake inhibitor». J. Pharmacol. Exp. Ther. 318 (2): 657–65. PMID 16675639. doi:10.1124/jpet.106.103382 
  10. ↑ a b c Vaishnavi SN, Nemeroff CB, Plott SJ, Rao SG, Kranzler J, Owens MJ (2004). «Milnacipran: a comparative analysis of human monoamine uptake and transporter binding affinity». Biol. Psychiatry. 55 (3): 320–2. PMID 14744476. doi:10.1016/j.biopsych.2003.07.006 
  11. ↑ Damaj, MI; Carroll, FI; Eaton, JB; Navarro, HA; Blough, BE; Mirza, S; Lukas, RJ; Martin, BR (September 2004). «Enantioselective effects of hydroxy metabolites of bupropion on behavior and on function of monoamine transporters and nicotinic receptors.». Molecular Pharmacology. 66 (3): 675–82. PMID 15322260. doi:10.1124/mol.104.001313  Verifique data em: |data= (ajuda)
  12. ↑ Baumann MH, Partilla JS, Lehner KR, Thorndike EB, Hoffman AF, Holy M, Rothman RB, Goldberg SR, Lupica CR, Sitte HH, Brandt SD, Tella SR, Cozzi NV, Schindler CW (2013). «Powerful cocaine-like actions of 3,4-methylenedioxypyrovalerone (MDPV), a principal constituent of psychoactive 'bath salts' products». Neuropsychopharmacology. 38 (4): 552–62. PMC 3572453 . PMID 23072836. doi:10.1038/npp.2012.204 
  13. ↑ Auclair AL, Martel JC, Assié MB, Bardin L, Heusler P, Cussac D, Marien M, Newman-Tancredi A, O'Connor JA, Depoortère R (2013). «Levomilnacipran (F2695), a norepinephrine-preferring SNRI: profile in vitro and in models of depression and anxiety». Neuropharmacology. 70: 338–47. PMID 23499664. doi:10.1016/j.neuropharm.2013.02.024  
  14. ↑ Zolkowska D, Jain R, Rothman RB, Partilla JS, Roth BL, Setola V, Prisinzano TE, Baumann MH (2009). «Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil». J. Pharmacol. Exp. Ther. 329 (2): 738–46. PMC 2672878 . PMID 19197004. doi:10.1124/jpet.108.146142 
  15. ↑ Gregori-Puigjané E, Setola V, Hert J, Crews BA, Irwin JJ, Lounkine E, Marnett L, Roth BL, Shoichet BK (2012). «Identifying mechanism-of-action targets for drugs and probes». Proc. Natl. Acad. Sci. U.S.A. 109 (28): 11178–83. Bibcode:2012PNAS..10911178G. PMC 3396511 . PMID 22711801. doi:10.1073/pnas.1204524109  
  16. ↑ Bymaster FP, McNamara RK, Tran PV (2003). «New approaches to developing antidepressants by enhancing monoaminergic neurotransmission». Expert Opin Investig Drugs. 12 (4): 531–43. PMID 12665410. doi:10.1517/13543784.12.4.531 
  17. ↑ Page ME, Cryan JF, Sullivan A, Dalvi A, Saucy B, Manning DR, Lucki I (2002). «Behavioral and neurochemical effects of 5-(4-[4-(5-Cyano-3-indolyl)-butyl)-butyl]-1-piperazinyl)-benzofuran-2-carboxamide (EMD 68843): a combined selective inhibitor of serotonin reuptake and 5-hydroxytryptamine(1A) receptor partial agonist». J. Pharmacol. Exp. Ther. 302 (3): 1220–7. PMID 12183683. doi:10.1124/jpet.102.034280 
  18. ↑ Bang-Andersen B, Ruhland T, Jørgensen M, Smith G, Frederiksen K, Jensen KG, Zhong H, Nielsen SM, Hogg S, Mørk A, Stensbøl TB (2011). «Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder». J. Med. Chem. 54 (9): 3206–21. PMID 21486038. doi:10.1021/jm101459g 
Obtida de "https://pt.wiki.x.io/w/index.php?title=Usuário(a):MikutoH/T/1&oldid=64580039"